Drug Discovery Research

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      Natural products and bacterial strains continue to provide a diverse and unique source of bioactive lead compounds for drug discovery.

 

    Isolation and identification of biologically active compounds can be a serious challenge which may have much more in common with scientific research work rather than with routine analytical task. In order to solve it, in addition to high performance equipment capabilities one should possess both an expertise in analytical chemistry and an ability to perform the most sophisticated scientific experiments. >>

 

PK/PD Method Development

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     I.B.S. is specialized in development of PK/PD HPLC assays with use of pre-column chemical derivatization and conventional HPLC-FLD or HPLC-UV equipment.

 

     Such approach is an ideal choice for biotech start-up companies since their primary requirements to a PK/PD assay are cost-effectiveness and robustness, along with necessary LOQ and specificity.

 

    Compared to widely used HPLC-MS approaches applied in development of PK/PD HPLC assays, HPLC-FLD with pre-column chemical derivatization posesses a number of distinct advantages. >>

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     See also:

 

        - HPLC Solutions

        - Speciality HPLC Columns